Research collaboration beyond national jurisdiction is one aspect of the globalisation of health research. It has potential to complement researchers in terms of research skills, equipment and lack of adequate numbers of potential research subjects. Collaboration at an equal level of partnership though desirable, may not be practicable. Sometimes, human research specimens must be transported from one country to other. Where this occurs, there should be clear understanding between the collaborating research institutions regarding issues of access and control of the (...) specimens as well as the duration of storage of specimens. The researchers have the duty to inform the research participants about specimen storage and transport across national boundaries. While obtaining informed consent from study subjects if specimens are to be stored beyond the life of the present study could be the ideal, there still remains significant challenges in a multi-cultural world. (shrink)

Open theists argue that God's relationship to time, as conceived in classical theism, is erroneous. They explain that it is contradictory for an atemporal being to act in a temporal universe, including experiencing its temporal successions. Contrary to the atemporalists, redemptive history has shown that God interacts with humans in time. This relational nature of God nullifies the classical notion of God as timelessly eternal. Therefore, it lacks a philosophical and theological basis. Because God is in time, He does not (...) know all future contingencies and, therefore, changes. This study examines open theism's appropriation of the A and B theories of time to the divine-human relationship. The study argues that divine temporality does not solve the tension of divine-human relationships, especially in relation to the future. Further, historical divine temporality does not negate the fact of divine atemporality. It mainly stems from God's choice to create temporal creatures and His relationship with them. Furthermore, if it is not logically and metaphysically contradictory for an omnipresent being to act in space, then it follows that an atemporal being can act in time. Whether time is understood from the metric or psychological point of view, it does not transcend God, and therefore, the limitation it places on human creatures with respect to the future does not apply to God. Lastly, although a few philosophers reject the notion of eternity as timelessly eternal, the doctrine has a philosophical and theological basis in the Scripture. (shrink)

This new edition brings Farquharson's authoritative 1944 translation up to date and includes a helpful introduction and notes for the student and general reader. Rutherford includes a selection of letters from Marcus to his tutor Fronto--most of which date from his earlier years--that offer personal detail and help to fill out the somber portrait of the emperor that is found in the Meditations.

HSÜN Tzu's essay on "Rectifying Terms" is justly considered a work of "great logical interest." For in this essay, one finds a remarkably modern concern with such topics as the rationale for having terms; the empirical and pragmatic bases for the classification of terms; the formation of generic and specific terms; the importance of observing established linguistic practices; the necessity of complying with proper standards for the institution, ratification, and regulation of the uses of language ; the nature of argumentative (...) discourse ; and the problems inherent in successful linguistic communication. A careful examination of some passages in other essays also suggests an awareness of the distinction between deductive, inductive, and analogical inferences, though Hsün Tzu provides us no explicit discussion of the nature of reasoning and its validating rules. (shrink)

Decisions by industry sponsors to end clinical trials early for commercial reasons have been the subject of controversy. I argue that the principal consideration in assessing these decisions ought to be the way in which the termination would affect the trial’s risk–benefit relationship. If there is not yet sufficient benefit to be gained from the study to offset the risks to which participants were exposed and it is expected that important scientific information would be obtained if the trial were continued, (...) early termination constitutes an unethical alteration of the risk−benefit relationship. This violates the grounds on which permission is given to conduct human research, patients consent to participate, and investigators agree to conduct studies. These knowable and avoidable changes in risk–benefit relationship should generally be seen as impermissible. (shrink)

This introduction to the basic ideas of structural proof theory contains a thorough discussion and comparison of various types of formalization of first-order logic. Examples are given of several areas of application, namely: the metamathematics of pure first-order logic (intuitionistic as well as classical); the theory of logic programming; category theory; modal logic; linear logic; first-order arithmetic and second-order logic. In each case the aim is to illustrate the methods in relatively simple situations and then apply them elsewhere in much (...) more complex settings. There are numerous exercises throughout the text. In general, the only prerequisite is a standard course in first-order logic, making the book ideal for graduate students and beginning researchers in mathematical logic, theoretical computer science and artificial intelligence. For the new edition, many sections have been rewritten to improve clarity, new sections have been added on cut elimination, and solutions to selected exercises have been included. (shrink)

The last epigrammatist named by Meleager as contributing to his Garland is Phanias, who, with Meleager's customary irrelevance, is said to be represented there by cornflowers. No inferences can be drawn from his place in the catalogue, which is neither chronological nor topographical in arrangement, and with one possible exception the epigrams give no hint of his home or date. In A.P. 6. 299.

UNTIL RECENT YEARS moral traditions have not been an important topic for moral philosophy. With few exceptions, attention has been directed to the problem of moral justification, to the search for universal criteria for the assessment of moral beliefs or judgments regardless of their traditional provenance. Generally, philosophers aspire to formulate "the view from nowhere." Since the publication of Alasdair MacIntyre's After Virtue there has been a revival of interest in the concept of a living, moral tradition, especially among moral (...) philosophers concerned with the possibility of an ethics of virtue or character as a viable alternative to the ethics of principle or, say, to deontological, utilitarian, or contractarian ethics. We must observe here that in the three decades prior to 1981, some moral philosophers displayed similar concern with tradition, although terms other than "tradition" were used, for example, "forms of life," "ways of life," "moral practices," and "moral community." Rawls's conception of reflective equilibrium is also developed with an eye on the notion of tradition. Indeed, Rawls has been quite explicit about his tradition-oriented approach to moral theory: "What justifies a conception of justice is not its being true to an order antecedent to and given to us, but its congruence with our deeper understanding of ourselves and our aspirations, and our realization that, given our history and the traditions embedded in our public life, it is the most reasonable doctrine.". (shrink)

Provability, Computability and Reflection.

The poem to which Callierges attached the title Hρακλσ ΛεοντοφῸνοσ from the narrative which occupies its last hundred lines falls into three sections, of which two have still, and all no doubt had originally, separate titles. In the first Herakles is found in conversation with a rustic who describes to him the estates of Augeias and accompanies him in search of that king. In the second the hero, in attendance on Augeias and his son Phyleus, inspects the royal flocks and (...) herds as they return at night to their folds and byres, and astonishes the spectators by the ease with which he repels the attack of a mighty bull. In the third Herakles and Phyleus are discovered on their way to the neighbouring town. Phyleus has heard from an Achaean stranger some account of the death of the Nemean lion, suspects that its slayer may have been his companion, and questions him. Herakles in reply tells the story. The poem exhibits the same conception of epic narrative as is seen in the authentic works of Theocritus. There is the eye for landscape and the attention to setting conspicuous in Id. 13 and in Part 2 of Id. 22: the keying down of the miraculous and heroic conspicuous in Id. 24: the easy command and constant memory of Homer which is in T. not confined to epic subjects. There is, too, at leaste point of contact with Callimachus. Part 1, as has been said, is occupied by a conversation between a friendly rustic and Herakles, who, we must suppose, is seeking Augeias in order to clean out his cattle-byres. We know next to nothing of what passed in the Hekale of Calhmachus between that heroine and Theseus on his way to deal with the bull of Marathon, and nothing of what passed in the Aetia between Molorchos and Herakles on his way to kill the lion of Nemea; but both Hekale and Molorchos were treated as poor countryfolk who befriend a hero bound on a heroic mission, and, whatever may have been the divergences of handling, the agreement between the two poets in this far from obvious method of attacking an epic theme is noteworthy. (shrink)

When Erysichthon, son of Triopas, persisted in felling trees in a grove sacred to Demeter the goddess inflicted on him an insatiable appetite, the consequences of which are brilliantly recounted by Callimachus in his sixth Hymn. Among them is a vain appeal from Triopas to his father Poseidon either to cure or else to feed his grandson, who has devoured the mules, the heifer which his mother was rearing for sacrifice, the racehorse, and the charger.

The scholiasts supposed that it was Zeus, not Strife, who dwells γαíνσ Έν ŕίζησι, and Paley has punctuated the line accordingly. I do not in any case doubt that he is wrong, but if the Theogony is evidence, he can almost be proved so. In the Theogony the γης ŕίσα;ι are a kind of suburb of Tartarus, from which the author does not very clearly distinguish them. In his useful though somewhat desultory gazetteer of those districts he says that Styx (...) dwells there apart from the gods, and that Iris only comes down when there are oaths to be administered in Olympus. Clearly Zeus is not at home in such a place. Strife herself is not enumerated in the Theogony among the residents, but her family is. Whatever she may be elsewhere, both in the Works and Days and in the Theogony she is the daughter of Night; and in the Theogony not only Night but also her two sons Sleep and Death reside in the district. Strife may appropriately keep them company. (shrink)

Some day, it may be, a betterGreek scholar and more skilful emendator than I will summon to hisaid from among scientists familiar with the Levant a botanist, aherbalist, a herpetologist, and an entomologist, empanel forconsultations a small body of medical men who have practised in theNear East, and produce an annotated text and translation of Nicander;and when this has been done it will be possible to read him, notindeed with pleasure, but with a good deal less labour and vexationthan attend (...) the process at present. Meanwhile, those whose dutyobliges them to struggle through the Theriaca andAlexipharmaca with the aids now available stand in no need ofthe injunction not to forget him which the author has appended tothose two poems. (shrink)

Some years ago, when discussing Theocr. 22. 177 sqq., I suggested that Theocritus had been a little careless in envisaging the circumstances which he is describing, and had written as though a duel normally resulted in the deaths of both combatants. That still seems to me the probable explanation of the difficulty with which I was dealing, and, as I then said, the oversight with which I charged Theocritus is venial enough, for in fact two deaths result from the particular (...) duel which he is about to describe. He is concerned with the drama, not with the setting, and if the setting proves to be of cardboard, the play is after all the thing. (shrink)